| 2020-10-17 12:00:0417/10/2020 |   Exeter Chiefs Women v Bristol Bears Women | 22 - 24 | |
| 2020-10-24 14:00:1924/10/2020 |  Bristol Bears Women v Loughborough Lightning | 5 - 12 | |
| 2020-10-31 14:00:3231/10/2020 |  Bristol Bears Women v Wasps Ladies | 10 - 64 | |
| 2020-11-07 14:30:5807/11/2020 |  Sale Sharks Women v Bristol Bears Women | 18 - 40 | |
| 2020-11-14 14:00:1114/11/2020 |  Bristol Bears Women v Gloucester-Hartpury Women | 3 - 28 | |
| 2020-11-28 14:00:2828/11/2020 |  Bristol Bears Women v Saracens Women | 10 - 36 | |
| 2020-12-05 15:00:2805/12/2020 |  Harlequins Women v Bristol Bears Women | 61 - 17 | |
| 2020-12-12 14:00:5812/12/2020 |  Bristol Bears Women v Worcester Warriors Women | 12 - 15 | |
| 2020-12-19 14:00:3719/12/2020 |  DMP Durham Sharks v Bristol Bears Women | 3 - 50 | |
| 2021-01-09 14:00:1509/01/2021 | Bristol Bears Women v Exeter Chiefs Women | 27 - 31 | |
| 2021-02-06 14:00:1006/02/2021 | Loughborough Lightning v Bristol Bears Women | 42 - 14 | |
| 2021-02-13 14:00:2513/02/2021 | Bristol Bears Women v Sale Sharks Women | 22 - 12 | |
| 2021-02-27 14:30:0327/02/2021 | Gloucester-Hartpury Women v Bristol Bears Women | 36 - 0 | |
| 2021-03-06 14:00:5006/03/2021 | Saracens Women v Bristol Bears Women | 53 - 7 | |
| 2021-03-20 14:00:0720/03/2021 | Bristol Bears Women v Harlequins Women | 7 - 62 | |
| 2021-03-28 14:00:5028/03/2021 | Worcester Warriors Women v Bristol Bears Women | 29 - 21 | |
| 2021-04-17 13:00:4317/04/2021 | Bristol Bears Women v DMP Durham Sharks | 17 - 34 | |
| 2021-05-08 14:00:0808/05/2021 | Wasps v Bristol Bears Women | 62 - 12 | |
