| 2020-10-10 14:00:1810/10/2020 |   Saracens Women v Worcester Warriors Women | 34 - 25 | |
| 2020-10-17 16:00:0717/10/2020 |  DMP Durham Sharks v Worcester Warriors Women | 5 - 58 | |
| 2020-10-24 14:00:1824/10/2020 |  Worcester Warriors Women v Wasps Ladies | 7 - 22 | |
| 2020-11-07 14:30:2107/11/2020 |  Exeter Chiefs Women v Worcester Warriors Women | 19 - 7 | |
| 2020-11-14 14:00:5514/11/2020 |  Worcester Warriors Women v Loughborough Lightning | 8 - 20 | |
| 2020-11-28 14:30:5228/11/2020 |  Sale Sharks Women v Worcester Warriors Women | 11 - 0 | |
| 2020-12-06 14:00:1106/12/2020 |  Worcester Warriors Women v Gloucester-Hartpury Women | 7 - 15 | |
| 2020-12-12 14:00:5812/12/2020 |  Bristol Bears Women v Worcester Warriors Women | 12 - 15 | |
| 2020-12-20 14:00:5820/12/2020 |  Worcester Warriors Women v Harlequins Women | 12 - 24 | |
| 2021-01-09 14:00:2009/01/2021 | Worcester Warriors Women v DMP Durham Sharks | 70 - 6 | |
| 2021-02-06 13:30:0306/02/2021 | Wasps v Worcester Warriors Women | 40 - 3 | |
| 2021-02-13 14:00:2613/02/2021 | Worcester Warriors Women v Exeter Chiefs Women | 10 - 17 | |
| 2021-02-27 14:00:2427/02/2021 | Loughborough Lightning v Worcester Warriors Women | 43 - 14 | |
| 2021-03-06 14:00:2506/03/2021 | Worcester Warriors Women v Sale Sharks Women | 31 - 21 | |
| 2021-03-20 14:00:0120/03/2021 | Gloucester-Hartpury Women v Worcester Warriors Women | 28 - 24 | |
| 2021-03-28 14:00:5028/03/2021 | Worcester Warriors Women v Bristol Bears Women | 29 - 21 | |
| 2021-04-17 13:00:4217/04/2021 | Harlequins Women v Worcester Warriors Women | 31 - 7 | |
| 2021-05-08 14:00:1308/05/2021 | Worcester Warriors Women v Saracens Women | 0 - 27 | |
